Biotech Breakthrough: IIT Guwahati’s New Path to Affordable Insulin

IIT Guwahati has secured two Indian patents for a pioneering insulin production system that could dramatically reduce costs and improve accessibility for millions of diabetes patients.

What’s the Innovation?

• Developed a novel bioprocess using Pseudomonas fluorescens, a safe and efficient bacterial system.
• Unlike traditional methods using E. coli, this system yields soluble insulin, simplifying production.
• Leverages Genetic, Metabolic, and Biochemical Engineering to optimize output and safety.

Key Advantages

• Lower production costs
• Higher yield of usable insulin.
• Potential to produce other therapeutic proteins and industrial enzymes using the same system.

Patent Details

Patent No.	Application No.	Date of Grant
568947	202431045821	22 July 2025
536416	202331058235	01 May 2024

Research Team

• Prof. Veeranki Venkata Dasu (Lead)
• Ansuman Sahoo (PMRF Scholar)
• Prabir Kumar Das
• Dr. MSRC Murthy
• Prof. Sanjukta Patra

With over 537 million adults affected by diabetes worldwide, and projections showing 1 in 8 adults may have diabetes by 2050, this innovation could reshape insulin accessibility and affordability.